search again

CYP2C9 Drug Metabolism Gene Test

Nationwide rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

Facilitymedian $263 · 10th–90th $141$7410%10%20%10th90th$263Professionalmedian $148 · 10th–90th $74$3240%20%10th90th$148$0.2$2.0$20.0$200.0$2.0K$20.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$275.42
Typical High
$707.95
Aetna
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$144.54
Typical High
$331.13
BCBS
Setting
Facility
Modifier
Global
Typical Low
$154.88
Median
$234.42
Typical High
$741.31
BCBS
Setting
Professional
Modifier
Global
Typical Low
$58.88
Median
$79.43
Typical High
$281.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$346.74
Typical High
$758.58
Cigna
Setting
Professional
Modifier
Global
Typical Low
$83.18
Median
$204.17
Typical High
$416.87
United
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$173.78
Typical High
$213.80
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$251.19