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CYP2C9 Drug Metabolism Gene Test

Nebraska rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

Facilitymedian $457 · 10th–90th $115$1,5490%10%10th90th$457Professionalmedian $115 · 10th–90th $105$1,1480%20%10th90th$115$100.0$200.0$500.0$1.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$524.81
Typical High
$1,548.82
Aetna
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$114.82
Typical High
$1,148.15
BCBS
Setting
Facility
Modifier
Global
Typical Low
$338.84
Median
$436.52
Typical High
$851.14
BCBS
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$275.42
Typical High
$288.40
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$331.13
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$263.03
Typical High
$831.76
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$501.19
Midlands
Setting
Professional
Modifier
Global
Typical Low
$363.08
Median
$363.08
Typical High
$363.08
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$165.96
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$104.71
Typical High
$478.63