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CYP2C9 Drug Metabolism Gene Test

West Virginia rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In West Virginia, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $148 from a physician practice, and about $339 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$148$87.10 to $251
FacilityA hospital or hospital-owned outpatient department$339$170 to $525

How much rates vary

Facilitymedian $339 · 10th to 90th $145 to $525Professionalmedian $148 · 10th to 90th $74 to $324
$100$200$500facility $339professional $148

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$144.54
Typical High
$144.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$144.54
Typical High
$147.91
CareSource
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$208.93
Typical High
$288.40
Cigna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$338.84
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$245.47
Typical High
$851.14
Highmark BCBS
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$741.31
Typical High
$741.31
United
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$104.71
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$87.10
Typical High
$323.59

Where West Virginia sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

West Virginia· 26th of 51

$174

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.