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CYP2C9 Drug Metabolism Gene Test

Maine rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$158

Typical negotiated rate. In Maine, October 2026.

Insurers have agreed to pay about $158 for this service. Most negotiated rates run $105 to $219.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $234 · 10th to 90th $170 to $617Professionalmedian $115 · 10th to 90th $89 to $251
$100$200$500$1Kfacility $234professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$141.25
Typical High
$141.25
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$229.09
Typical High
$616.60
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$104.71
Typical High
$141.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$275.42
Typical High
$398.11
Cigna
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$177.83
Typical High
$177.83
Harvard Pilgrim
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$173.78
Typical High
$309.03
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$141.25
Typical High
$141.25
United
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$309.03

Where Maine sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 32nd of 51

$158

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.