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CYP2C9 Drug Metabolism Gene Test

Maine rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Maine, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $282 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$141 to $174
FacilityA hospital or hospital-owned outpatient department$282$174 to $617

How much rates vary

Facilitymedian $282 · 10th to 90th $174 to $676Professionalmedian $174 · 10th to 90th $105 to $195
$100$200$500facility $282professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$141.25
Typical High
$173.78
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$204.17
Median
$616.60
Typical High
$676.08
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$104.71
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$398.11
Median
$398.11
Typical High
$398.11
Cigna
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$173.78
Typical High
$177.83
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$208.93
Martin's Point
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$776.25
Martin's Point
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$173.78
Typical High
$194.98
United
Setting
Facility
Modifier
Global
Typical Low
$446.68
Median
$446.68
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$269.15

Where Maine sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maine· 21st of 51

$174

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.