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CYP2C9 Drug Metabolism Gene Test

Massachusetts rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

Facilitymedian $347 · 10th–90th $129$5620%10%10th90th$347Professionalmedian $174 · 10th–90th $105$4370%20%40%10th90th$174$100.0$500.0$2.0K$10.0K$50.0K

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$338.84
Typical High
$562.34
Aetna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$141.25
Typical High
$524.81
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$199.53
Typical High
$575.44
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$588.84
BCBS
Setting
Facility
Modifier
Global
Typical Low
$275.42
Median
$346.74
Typical High
$501.19
BCBS
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$165.96
Typical High
$169.82
Cigna
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$213.80
Typical High
$338.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$186.21
Typical High
$457.09
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$251.19
Typical High
$295.12
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$316.23
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$199.53
Typical High
$575.44
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$588.84
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$389.05