go back

CYP2C9 Drug Metabolism Gene Test

South Dakota rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

Facilitymedian $331 · 10th–90th $200$3310%50%10th$331Professionalmedian $263 · 10th–90th $117$4570%10%10th90th$263$100.0$200.0$500.0

Distribution of negotiated rates across all payers (price axis is log-scale). Facility and professional rates are different services and are charted separately. Need provider-level prices? Contact us.

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$199.53
Typical High
$199.53
Aetna
Setting
Professional
Modifier
Global
Typical Low
$117.49
Median
$134.90
Typical High
$165.96
Avera
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$331.13
Typical High
$331.13
Cigna
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$331.13
Typical High
$416.87
Medica
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$199.53
Typical High
$489.78
Medica
Setting
Professional
Modifier
Global
Typical Low
$89.13
Median
$89.13
Typical High
$870.96
Sanford Health Plan
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$407.38
Typical High
$478.63
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$229.09
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78