go back

CYP2C9 Drug Metabolism Gene Test

Missouri rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$170

Typical negotiated rate. In Missouri, July 2026.

Insurers have agreed to pay about $170 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $229 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$89.13 to $200
FacilityA hospital or hospital-owned outpatient department$229$174 to $302

How much rates vary

Facilitymedian $229 · 10th to 90th $148 to $407Professionalmedian $151 · 10th to 90th $69 to $309
$20$50$100$200$500facility $229professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$295.12
Typical High
$338.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$169.82
Typical High
$346.74
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$616.60
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$19.05
Median
$74.13
Typical High
$275.42
BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$173.78
Typical High
$194.98
Cigna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$338.84
Typical High
$724.44
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$138.04
Typical High
$251.19
Medica
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$208.93
Typical High
$831.76
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$870.96
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$234.42

Where Missouri sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Missouri· 26th of 51

$170

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.