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CYP2C9 Drug Metabolism Gene Test

Arizona rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$141

Typical negotiated rate. In Arizona, October 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $117 from a physician practice, and about $380 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$117$74.13 to $174
FacilityA hospital or hospital-owned outpatient department$380$191 to $575

How much rates vary

Facilitymedian $380 · 10th to 90th $110 to $759Professionalmedian $117 · 10th to 90th $74 to $871
$100$200$500$1Kfacility $380professional $117

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$562.34
Typical High
$912.01
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$117.49
Typical High
$131.83
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$58.88
Median
$58.88
Typical High
$66.07
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$23.44
Median
$23.44
Typical High
$26.30
BCBS Arizona
Setting
Facility
Modifier
None
Typical Low
$117.49
Median
$512.86
Typical High
$758.58
BCBS Arizona
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$173.78
Typical High
$302.00
Cigna
Setting
Facility
Modifier
None
Typical Low
$85.11
Median
$338.84
Typical High
$489.78
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$169.82
Typical High
$676.08
Medica
Setting
Facility
Modifier
None
Typical Low
$117.49
Median
$141.25
Typical High
$302.00
Medica
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$870.96
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$104.71

Where Arizona sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 38th of 51

$141

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.