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CYP2C9 Drug Metabolism Gene Test

Hawaii rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$209

Typical negotiated rate. In Hawaii, October 2026.

Insurers have agreed to pay about $209 for this service. Most negotiated rates run $186 to $229.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Professionalmedian $209 · 10th to 90th $174 to $263
$200professional $209

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Cigna
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
HMSA
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$186.21
Typical High
$251.19
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$208.93
Typical High
$338.84
United
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$263.03
University Health Alliance
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$204.17
Typical High
$323.59

Where Hawaii sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Hawaii· 8th of 51

$209

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.