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CYP2C9 Drug Metabolism Gene Test

Georgia rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$200

Typical negotiated rate. In Georgia, October 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $195 from a physician practice, and about $204 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$195$79.43 to $257
FacilityA hospital or hospital-owned outpatient department$204$174 to $282

How much rates vary

Facilitymedian $204 · 10th to 90th $132 to $603Professionalmedian $195 · 10th to 90th $44 to $372
$20$50$100$200$500facility $204professional $195

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$117.49
Median
$117.49
Typical High
$309.03
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$134.90
Typical High
$165.96
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$199.53
Typical High
$602.56
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$43.65
Median
$218.78
Typical High
$346.74
CareSource
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$229.09
Typical High
$234.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$338.84
Typical High
$537.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$87.10
Median
$269.15
Typical High
$691.83
Kaiser Permanente
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$239.88
Typical High
$331.13
Oscar Health
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$213.80
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$371.54
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$57.54
Median
$67.61
Typical High
$83.18
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$23.44
Median
$27.54
Typical High
$33.88

Where Georgia sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Georgia· 12th of 51

$200

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.