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CYP2C9 Drug Metabolism Gene Test

Alabama rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Alabama, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$77.62 to $200
FacilityA hospital or hospital-owned outpatient department$174$174 to $174

How much rates vary

Facilitymedian $174 · 10th to 90th $174 to $174Professionalmedian $105 · 10th to 90th $74 to $200
$100$200$500facility $174professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$269.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$199.53
Typical High
$199.53
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$100.00
Typical High
$100.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$27.54
Median
$39.81
Typical High
$39.81
BCBS Alabama
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
BCBS Alabama
Setting
Professional
Modifier
21 + 22 · Increased work + 24 · Unrelated visit after surgery + 31
Typical Low
$25.70
Median
$37.15
Typical High
$37.15
Cigna
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$147.91
Typical High
$549.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$66.07
Median
$83.18
Typical High
$724.44
United
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$158.49
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$95.50
Typical High
$104.71

Where Alabama sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alabama· 27th of 51

$174

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.