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CYP2C9 Drug Metabolism Gene Test

Kansas rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Kansas, October 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $174 from a physician practice, and about $182 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$174$105 to $186
FacilityA hospital or hospital-owned outpatient department$182$138 to $204

How much rates vary

Facilitymedian $182 · 10th to 90th $129 to $204Professionalmedian $174 · 10th to 90th $105 to $437
$100$200$500facility $182professional $174

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$120.23
Median
$208.93
Typical High
$323.59
Aetna
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$173.78
Typical High
$186.21
BCBS Kansas
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$138.04
Typical High
$204.17
BCBS Kansas
Setting
Professional
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Cigna
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$194.98
Typical High
$707.95
Cigna
Setting
Professional
Modifier
None
Typical Low
$81.28
Median
$251.19
Typical High
$331.13
Medica
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$186.21
Typical High
$199.53
Medica
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$104.71
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$295.12
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$75.86
Median
$87.10
Typical High
$93.33
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.20
Median
$34.67
Typical High
$37.15

Where Kansas sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kansas· 19th of 51

$174

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.