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CYP2C9 Drug Metabolism Gene Test

South Carolina rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$141

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$135 to $151
FacilityA hospital or hospital-owned outpatient department$324$135 to $562

How much rates vary

Facilitymedian $324 · 10th to 90th $135 to $832Professionalmedian $135 · 10th to 90th $105 to $204
$100$200$500$1Kfacility $324professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$123.03
Median
$426.58
Typical High
$831.76
Aetna
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$158.49
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,071.52
Median
$1,071.52
Typical High
$1,148.15
BCBS
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$204.17
Typical High
$363.08
Cigna
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$524.81
Typical High
$1,000.00
Cigna
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$81.28
Typical High
$181.97
Medcost
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$165.96
Typical High
$316.23
United
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$173.78

Where South Carolina sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

South Carolina· 47th of 51

$141

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.