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CYP2C9 Drug Metabolism Gene Test

New York rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$170

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $170 for this service. The price depends on where it is billed: about $141 from a physician practice, and about $288 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$141$95.50 to $204
FacilityA hospital or hospital-owned outpatient department$288$174 to $407

How much rates vary

Facilitymedian $288 · 10th to 90th $141 to $479Professionalmedian $141 · 10th to 90th $69 to $316
$50$100$200$500$1Kfacility $288professional $141

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$302.00
Typical High
$478.63
Aetna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$147.91
Typical High
$316.23
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$457.09
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$69.18
Typical High
$316.23
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$173.78
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$371.54
Typical High
$501.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$229.09
Typical High
$851.14
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$288.40
Typical High
$676.08
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$104.71
Median
$144.54
Typical High
$316.23
Excellus BCBS
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$107.15
Typical High
$107.15
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$165.96
Typical High
$204.17
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$257.04
Typical High
$50,118.72
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$173.78
Typical High
$323.59
United
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$173.78
Typical High
$263.03
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$134.90
Typical High
$275.42
Univera
Setting
Facility
Modifier
Global
Typical Low
$107.15
Median
$107.15
Typical High
$186.21
Univera
Setting
Professional
Modifier
Global
Typical Low
$107.15
Median
$165.96
Typical High
$346.74

Where New York sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

New York· 25th of 51

$170

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.