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CYP2C9 Drug Metabolism Gene Test

Rhode Island rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$151

Typical negotiated rate. In Rhode Island, October 2026.

Insurers have agreed to pay about $151 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $209 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$105 to $155
FacilityA hospital or hospital-owned outpatient department$209$174 to $257

How much rates vary

Facilitymedian $209 · 10th to 90th $158 to $479Professionalmedian $132 · 10th to 90th $91 to $240
$100$200$500facility $209professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$154.88
Typical High
$154.88
BCBS Rhode Island
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$199.53
Typical High
$257.04
BCBS Rhode Island
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$131.83
Typical High
$165.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$309.03
Median
$478.63
Typical High
$537.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$97.72
Median
$239.88
Typical High
$239.88
United
Setting
Facility
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$288.40

Where Rhode Island sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 36th of 51

$151

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.