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CYP2C9 Drug Metabolism Gene Test

Rhode Island rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$155

Typical negotiated rate. In Rhode Island, July 2026.

Insurers have agreed to pay about $155 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $257 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$123 to $155
FacilityA hospital or hospital-owned outpatient department$257$209 to $380

How much rates vary

Facilitymedian $257 · 10th to 90th $174 to $1,000Professionalmedian $132 · 10th to 90th $112 to $174
$100$200$500$1Kfacility $257professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$380.19
Typical High
$1,000.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$123.03
Typical High
$158.49
BCBS
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$199.53
Typical High
$257.04
BCBS
Setting
Professional
Modifier
Global
Typical Low
$123.03
Median
$131.83
Typical High
$165.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$478.63
Typical High
$537.03
Cigna
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$100.00
Typical High
$239.88
United
Setting
Facility
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$245.47
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$251.19

Where Rhode Island sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 39th of 51

$155

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.