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CYP2C9 Drug Metabolism Gene Test

Florida rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$123

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $123 for this service. The price depends on where it is billed: about $105 from a physician practice, and about $324 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$105$74.13 to $155
FacilityA hospital or hospital-owned outpatient department$324$224 to $324

How much rates vary

Facilitymedian $324 · 10th to 90th $138 to $324Professionalmedian $105 · 10th to 90th $62 to $209
$10$20$50$100$200$500facility $324professional $105

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$104.71
Median
$131.83
Typical High
$354.81
Aetna
Setting
Professional
Modifier
None
Typical Low
$93.33
Median
$123.03
Typical High
$154.88
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$52.48
Median
$61.66
Typical High
$77.62
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$20.89
Median
$24.55
Typical High
$30.90
Ambetter
Setting
Professional
Modifier
None
Typical Low
$107.15
Median
$107.15
Typical High
$107.15
AvMed
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$173.78
Typical High
$213.80
AvMed
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$93.33
Median
$141.25
Typical High
$707.95
Cigna
Setting
Professional
Modifier
None
Typical Low
$83.18
Median
$123.03
Typical High
$316.23
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$323.59
Median
$323.59
Typical High
$323.59
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$104.71
Typical High
$208.93
Molina
Setting
Professional
Modifier
None
Typical Low
$60.26
Median
$60.26
Typical High
$218.78
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$74.13
Typical High
$239.88
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$162.18
Median
$173.78
Typical High
$173.78

Where Florida sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 47th of 51

$123

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.