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CYP2C9 Drug Metabolism Gene Test

Maryland rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$132

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $132 for this service. Most negotiated rates run $126 to $148.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $74 · 10th to 90th $74 to $447Professionalmedian $132 · 10th to 90th $79 to $200
$100$200$500$1Kfacility $74professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$144.54
Typical High
$190.55
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$125.89
Typical High
$154.88
Cigna
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$107.15
Typical High
$309.03
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$208.93
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$446.68
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$79.43
Typical High
$154.88
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$138.04
Typical High
$138.04

Where Maryland sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Maryland· 51st of 51

$132

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.