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CYP2C9 Drug Metabolism Gene Test

Connecticut rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $123 from a physician practice, and about $275 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$123$105 to $229
FacilityA hospital or hospital-owned outpatient department$275$174 to $355

How much rates vary

Facilitymedian $275 · 10th to 90th $174 to $490Professionalmedian $123 · 10th to 90th $95 to $389
$100$200$500$1Kfacility $275professional $123

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$251.19
Typical High
$489.78
Aetna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$123.03
Typical High
$389.05
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$275.42
Typical High
$467.74
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$89.13
Typical High
$416.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$275.42
Typical High
$630.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$97.72
Median
$208.93
Typical High
$363.08
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$181.97
Typical High
$281.84
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$144.54
Typical High
$263.03

Where Connecticut sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 18th of 51

$174

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.