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CYP2C9 Drug Metabolism Gene Test

Tennessee rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$174

Typical negotiated rate. In Tennessee, October 2026.

Insurers have agreed to pay about $174 for this service. Most negotiated rates run $105 to $372.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $355 · 10th to 90th $117 to $513Professionalmedian $155 · 10th to 90th $79 to $1,318
$50$100$200$500$1Kfacility $355professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$131.83
Median
$138.04
Typical High
$269.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$138.04
Typical High
$177.83
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$66.07
Median
$69.18
Typical High
$100.00
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.30
Median
$27.54
Typical High
$39.81
BCBS Tennessee
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$363.08
Typical High
$549.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$95.50
Typical High
$239.88
Lucent Health
Setting
Professional
Modifier
None
Typical Low
$870.96
Median
$1,318.26
Typical High
$1,318.26
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$173.78

Where Tennessee sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 20th of 51

$174

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.