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CYP2C9 Drug Metabolism Gene Test

Tennessee rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$148

Typical negotiated rate. In Tennessee, July 2026.

Insurers have agreed to pay about $148 for this service. The price depends on where it is billed: about $138 from a physician practice, and about $282 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$138$132 to $174
FacilityA hospital or hospital-owned outpatient department$282$158 to $575

How much rates vary

Facilitymedian $282 · 10th to 90th $132 to $759Professionalmedian $138 · 10th to 90th $91 to $209
$50$100$200$500$1Kfacility $282professional $138

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$478.63
Typical High
$758.58
Aetna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$138.04
Typical High
$199.53
BCBS
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$173.78
Typical High
$173.78
Cigna
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$363.08
Typical High
$588.84
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$102.33
Typical High
$239.88
Lucent Health
Setting
Facility
Modifier
Global
Typical Low
$831.76
Median
$831.76
Typical High
$831.76
Lucent Health
Setting
Professional
Modifier
Global
Typical Low
$870.96
Median
$1,318.26
Typical High
$1,318.26
United
Setting
Facility
Modifier
Global
Typical Low
$74.13
Median
$173.78
Typical High
$173.78
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$173.78

Where Tennessee sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Tennessee· 43rd of 51

$148

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.