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CYP2C9 Drug Metabolism Gene Test

Arkansas rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$200

Typical negotiated rate. In Arkansas, October 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $148 from a physician practice, and about $200 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$148$105 to $219
FacilityA hospital or hospital-owned outpatient department$200$200 to $257

How much rates vary

Facilitymedian $200 · 10th to 90th $174 to $275Professionalmedian $148 · 10th to 90th $91 to $219
$100$200facility $200professional $148

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$218.78
Median
$218.78
Typical High
$269.15
Aetna
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$218.78
Typical High
$218.78
BCBS Arkansas
Setting
Facility
Modifier
None
Typical Low
$199.53
Median
$199.53
Typical High
$275.42
BCBS Arkansas
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$218.78
Typical High
$218.78
CareSource
Setting
Professional
Modifier
None
Typical Low
$114.82
Median
$114.82
Typical High
$173.78
Cigna
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$223.87
Typical High
$323.59
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$91.20
Typical High
$263.03
United
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$173.78
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$177.83
4 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$109.65
Typical High
$109.65
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.18
Median
$43.65
Typical High
$43.65
Ambetter
Setting
Professional
Modifier
59 · Distinct service
Typical Low
$147.91
Median
$147.91
Typical High
$173.78
Qualchoice
Setting
Professional
Modifier
59 · Distinct service
Typical Low
$169.82
Median
$169.82
Typical High
$199.53

Where Arkansas sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arkansas· 11th of 51

$200

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.