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CYP2C9 Drug Metabolism Gene Test

Oklahoma rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$166

Typical negotiated rate. In Oklahoma, July 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $174 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$89.13 to $182
FacilityA hospital or hospital-owned outpatient department$174$132 to $234

How much rates vary

Facilitymedian $174 · 10th to 90th $129 to $447Professionalmedian $132 · 10th to 90th $74 to $219
$100$200$500facility $174professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$173.78
Typical High
$446.68
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$131.83
Typical High
$218.78
BCBS
Setting
Professional
Modifier
Global
Typical Low
$165.96
Median
$165.96
Typical High
$165.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$467.74
Typical High
$478.63
Cigna
Setting
Professional
Modifier
Global
Typical Low
$77.62
Median
$91.20
Typical High
$257.04
Medica
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$218.78
Typical High
$295.12
Medica
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$63.10
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$74.13
Typical High
$114.82

Where Oklahoma sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 28th of 51

$166

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.