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CYP2C9 Drug Metabolism Gene Test

Oklahoma rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$129

Typical negotiated rate. In Oklahoma, October 2026.

Insurers have agreed to pay about $129 for this service. The price depends on where it is billed: about $89.13 from a physician practice, and about $174 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$89.13$74.13 to $174
FacilityA hospital or hospital-owned outpatient department$174$132 to $245

How much rates vary

Facilitymedian $174 · 10th to 90th $129 to $479Professionalmedian $89 · 10th to 90th $74 to $871
$100$200$500facility $174professional $89

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$144.54
Typical High
$162.18
Aetna
Setting
Professional
Modifier
None
Typical Low
$6.03
Median
$128.82
Typical High
$186.21
BCBS
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$165.96
Typical High
$190.55
Cigna
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$478.63
Typical High
$478.63
Cigna
Setting
Professional
Modifier
None
Typical Low
$77.62
Median
$77.62
Typical High
$128.82
Medica
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$229.09
Typical High
$302.00
Medica
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$173.78
Typical High
$870.96
United
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$74.13
Typical High
$114.82

Where Oklahoma sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 46th of 51

$129

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.