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CYP2C9 Drug Metabolism Gene Test

Alaska rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$389

Typical negotiated rate. In Alaska, October 2026.

Insurers have agreed to pay about $389 for this service. The price depends on where it is billed: about $389 from a physician practice, and about $759 from a hospital or other facility.

Few insurers publish rates for this combination, so treat this figure as a rough guide.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$389$347 to $389
FacilityA hospital or hospital-owned outpatient department$759$589 to $1,259

How much rates vary

Facilitymedian $759 · 10th to 90th $479 to $2,042Professionalmedian $389 · 10th to 90th $158 to $589
$100$200$500$1K$2Kfacility $759professional $389

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$1,230.27
Typical High
$2,137.96
Aetna
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$588.84
Typical High
$2,137.96
Cigna
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$478.63
Typical High
$478.63
Moda Health
Setting
Facility
Modifier
None
Typical Low
$588.84
Median
$831.76
Typical High
$2,041.74
Moda Health
Setting
Professional
Modifier
None
Typical Low
$117.49
Median
$173.78
Typical High
$1,258.93
Premera BCBS
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$660.69
Typical High
$831.76
Premera BCBS
Setting
Professional
Modifier
None
Typical Low
$263.03
Median
$389.05
Typical High
$389.05
Providence
Setting
Facility
Modifier
None
Typical Low
$478.63
Median
$588.84
Typical High
$851.14
Providence
Setting
Professional
Modifier
None
Typical Low
$158.49
Median
$158.49
Typical High
$158.49
United
Setting
Professional
Modifier
None
Typical Low
$104.71
Median
$346.74
Typical High
$524.81

Where Alaska sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Alaska· 1st of 51

$389

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.