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CYP2C9 Drug Metabolism Gene Test

Michigan rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$166

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $166 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $166 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$132 to $166
FacilityA hospital or hospital-owned outpatient department$166$166 to $209

How much rates vary

Facilitymedian $166 · 10th to 90th $158 to $302Professionalmedian $145 · 10th to 90th $95 to $209
$100$200facility $166professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$165.96
Typical High
$302.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$165.96
Typical High
$208.93
BCBS
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$199.53
Typical High
$346.74
BCBS
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$131.83
Typical High
$131.83
CareSource
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$173.78
CareSource
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$190.55
Typical High
$234.42
Cigna
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$97.72
Typical High
$245.47
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$177.83
Typical High
$407.38
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$169.82
Typical High
$234.42
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$204.17
Typical High
$389.05
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$104.71
Typical High
$173.78

Where Michigan sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 29th of 51

$166

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.