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CYP2C9 Drug Metabolism Gene Test

Ohio rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated October 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$141

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $141 for this service. The price depends on where it is billed: about $91.20 from a physician practice, and about $234 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$91.20$69.18 to $155
FacilityA hospital or hospital-owned outpatient department$234$186 to $324

How much rates vary

Facilitymedian $234 · 10th to 90th $162 to $479Professionalmedian $91 · 10th to 90th $69 to $282
$100$200$500$1Kfacility $234professional $91

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$165.96
Median
$331.13
Typical High
$588.84
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$83.18
Median
$165.96
Typical High
$295.12
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$33.11
Median
$67.61
Typical High
$117.49
Aetna
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$141.25
Typical High
$575.44
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$69.18
Median
$69.18
Typical High
$288.40
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.18
Median
$28.18
Typical High
$114.82
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$204.17
Typical High
$323.59
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$69.18
Median
$69.18
Typical High
$229.09
CareSource
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$173.78
Typical High
$234.42
Cigna
Setting
Facility
Modifier
None
Typical Low
$169.82
Median
$229.09
Typical High
$724.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$79.43
Typical High
$316.23
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$234.42
Typical High
$724.44
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$79.43
Typical High
$316.23
Molina
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$158.49
Typical High
$218.78
SummaCare
Setting
Professional
Modifier
None
Typical Low
$147.91
Median
$213.80
Typical High
$275.42
United
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$158.49
Typical High
$263.03
United
Setting
Professional
Modifier
None
Typical Low
$74.13
Median
$104.71
Typical High
$251.19

Where Ohio sits

The same service costs 3.4 times more in Alaska than in Nebraska. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 39th of 51

$141

AK $389NE $115

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.