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CYP2C9 Drug Metabolism Gene Test

Virginia rates for HCPCS 81227

Examines the CYP2C9 gene, which carries the instructions for a liver enzyme that breaks down a specific set of medicines. The test checks for the common variants and reports whether a person clears those drugs normally or more slowly than usual, which affects the dose they need.

Rates data updated July 2026.

How much does CYP2C9 Drug Metabolism Gene Test cost?

$158

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $132 from a physician practice, and about $200 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$132$79.43 to $151
FacilityA hospital or hospital-owned outpatient department$200$174 to $437

How much rates vary

Facilitymedian $200 · 10th to 90th $151 to $776Professionalmedian $132 · 10th to 90th $69 to $331
$100$200$500$1K$2K$5K$10Kfacility $200professional $132

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$389.05
Typical High
$776.25
Aetna
Setting
Professional
Modifier
Global
Typical Low
$131.83
Median
$147.91
Typical High
$436.52
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$173.78
Typical High
$691.83
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$69.18
Typical High
$117.49
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$204.17
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$177.83
Median
$436.52
Typical High
$794.33
Cigna
Setting
Professional
Modifier
Global
Typical Low
$87.10
Median
$107.15
Typical High
$295.12
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$190.55
Typical High
$245.47
Medcost
Setting
Facility
Modifier
Global
Typical Low
$141.25
Median
$169.82
Typical High
$302.00
Medcost
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$151.36
Typical High
$363.08
Sentara
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$229.09
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$229.09
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$173.78
Typical High
$208.93
United
Setting
Professional
Modifier
Global
Typical Low
$74.13
Median
$89.13
Typical High
$199.53

Where Virginia sits

The same service costs 3.0 times more in Alaska than in Maryland. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Virginia· 31st of 51

$158

AK $389MD $132

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.