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SEPT9 Methylation Blood Test for Colon Cancer

South Carolina rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$155

Typical negotiated rate. In South Carolina, July 2026.

Insurers have agreed to pay about $155 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $355 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$151 to $158
FacilityA hospital or hospital-owned outpatient department$355$155 to $617

How much rates vary

Facilitymedian $355 · 10th to 90th $151 to $912Professionalmedian $151 · 10th to 90th $83 to $200
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $355professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$151.36
Median
$467.74
Typical High
$912.01
Aetna
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$151.36
Typical High
$173.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$1,174.90
Median
$1,174.90
Typical High
$1,258.93
BCBS
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$204.17
Typical High
$288.40
Cigna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$489.78
Typical High
$1,096.48
Cigna
Setting
Professional
Modifier
Global
Typical Low
$38.02
Median
$72.44
Typical High
$204.17
Medcost
Setting
Facility
Modifier
Global
Typical Low
$79.43
Median
$173.78
Typical High
$257.04
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$190.55
Typical High
$229.09
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$81.28
Typical High
$173.78

Where South Carolina sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

South Carolina $155 · 38th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.