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SEPT9 Methylation Blood Test for Colon Cancer

Mississippi rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$204

Typical negotiated rate. In Mississippi, July 2026.

Insurers have agreed to pay about $204 for this service. The price depends on where it is billed: about $204 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$204$145 to $347
FacilityA hospital or hospital-owned outpatient department$295$191 to $347

How much rates vary

Facilitymedian $295 · 10th to 90th $100 to $347Professionalmedian $204 · 10th to 90th $83 to $389
$50.0$100.0$200.0$500.0facility $295professional $204

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$346.74
Typical High
$389.05
Aetna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$218.78
Typical High
$389.05
BCBS
Setting
Facility
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
BCBS
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$295.12
Typical High
$295.12
Cigna
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$125.89
Typical High
$144.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$87.10
Typical High
$213.80
United
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$173.78
Typical High
$190.55
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$83.18
Typical High
$186.21

Where Mississippi sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Mississippi $204 · 9th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.