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SEPT9 Methylation Blood Test for Colon Cancer

Connecticut rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$105

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $105 for this service. Most negotiated rates run $83.18 to $191.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $191 · 10th to 90th $63 to $479Professionalmedian $98 · 10th to 90th $55 to $240
$50$100$200$500facility $191professional $98

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$54.95
Typical High
$58.88
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$63.10
Median
$134.90
Typical High
$467.74
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$83.18
Median
$97.72
Typical High
$162.18
Cigna
Setting
Facility
Modifier
None
Typical Low
$72.44
Median
$190.55
Typical High
$707.95
Cigna
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$107.15
Typical High
$389.05
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$112.20
Median
$199.53
Typical High
$309.03
United
Setting
Professional
Modifier
None
Typical Low
$51.29
Median
$114.82
Typical High
$245.47
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$22.91
Median
$27.54
Typical High
$29.51
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$9.12
Median
$10.96
Typical High
$11.75

Where Connecticut sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 48th of 51

$105

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.