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SEPT9 Methylation Blood Test for Colon Cancer

Connecticut rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$174

Typical negotiated rate. In Connecticut, July 2026.

Insurers have agreed to pay about $174 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $275 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$54.95 to $209
FacilityA hospital or hospital-owned outpatient department$275$191 to $407

How much rates vary

Facilitymedian $275 · 10th to 90th $115 to $537Professionalmedian $115 · 10th to 90th $46 to $427
$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $275professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$275.42
Typical High
$537.03
Aetna
Setting
Professional
Modifier
Global
Typical Low
$44.67
Median
$128.82
Typical High
$426.58
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$302.00
Typical High
$512.86
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$93.33
Typical High
$245.47
Cigna
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$309.03
Typical High
$707.95
Cigna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$128.82
Typical High
$354.81
ConnectiCare
Setting
Professional
Modifier
Global
Typical Low
$112.20
Median
$199.53
Typical High
$263.03
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
United
Setting
Professional
Modifier
Global
Typical Low
$51.29
Median
$114.82
Typical High
$288.40

Where Connecticut sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Connecticut $174 · 22nd of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.