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SEPT9 Methylation Blood Test for Colon Cancer

Arizona rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$129

Typical negotiated rate. In Arizona, October 2026.

Insurers have agreed to pay about $129 for this service. The price depends on where it is billed: about $115 from a physician practice, and about $417 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$115$81.28 to $182
FacilityA hospital or hospital-owned outpatient department$417$209 to $631

How much rates vary

Facilitymedian $417 · 10th to 90th $123 to $832Professionalmedian $115 · 10th to 90th $35 to $955
$50$100$200$500$1Kfacility $417professional $115

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$616.60
Typical High
$1,000.00
Aetna
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$128.82
Typical High
$128.82
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$64.57
Median
$64.57
Typical High
$64.57
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$25.70
Median
$25.70
Typical High
$25.70
BCBS Arizona
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$562.34
Typical High
$831.76
BCBS Arizona
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$190.55
Typical High
$331.13
Cigna
Setting
Facility
Modifier
None
Typical Low
$64.57
Median
$380.19
Typical High
$537.03
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$87.10
Typical High
$295.12
Medica
Setting
Facility
Modifier
None
Typical Low
$128.82
Median
$154.88
Typical High
$331.13
Medica
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$81.28
Typical High
$954.99
United
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$81.28
Typical High
$114.82

Where Arizona sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Arizona· 34th of 51

$129

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.