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SEPT9 Methylation Blood Test for Colon Cancer

Arizona rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$145

Typical negotiated rate. In Arizona, July 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$81.28 to $155
FacilityA hospital or hospital-owned outpatient department$295$138 to $724

How much rates vary

Facilitymedian $295 · 10th to 90th $126 to $832Professionalmedian $129 · 10th to 90th $46 to $219
$1.0$10.0$100.0$1.0Kfacility $295professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$295.12
Typical High
$831.76
Aetna
Setting
Professional
Modifier
Global
Typical Low
$69.18
Median
$128.82
Typical High
$218.78
BCBS
Setting
Facility
Modifier
Global
Typical Low
$131.83
Median
$549.54
Typical High
$1,023.29
BCBS
Setting
Professional
Modifier
Global
Typical Low
$181.97
Median
$190.55
Typical High
$1,318.26
Cigna
Setting
Facility
Modifier
Global
Typical Low
$53.70
Median
$186.21
Typical High
$630.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$47.86
Median
$102.33
Typical High
$186.21
Medica
Setting
Facility
Modifier
Global
Typical Low
$128.82
Median
$190.55
Typical High
$331.13
Medica
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$81.28
Typical High
$954.99
United
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$190.55
Typical High
$218.78
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$81.28
Typical High
$114.82

Where Arizona sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Arizona $145 · 43rd of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.