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SEPT9 Methylation Blood Test for Colon Cancer

Wyoming rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$240

Typical negotiated rate. In Wyoming, October 2026.

Insurers have agreed to pay about $240 for this service. The price depends on where it is billed: about $240 from a physician practice, and about $240 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$240$191 to $617
FacilityA hospital or hospital-owned outpatient department$240$191 to $288

How much rates vary

Facilitymedian $240 · 10th to 90th $191 to $380Professionalmedian $240 · 10th to 90th $81 to $617
$50$100$200$500facility $240professional $240

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Aetna
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
BCBS Wyoming
Setting
Facility
Modifier
None
Typical Low
$239.88
Median
$239.88
Typical High
$288.40
BCBS Wyoming
Setting
Professional
Modifier
None
Typical Low
$239.88
Median
$295.12
Typical High
$616.60
BCBS Wyoming
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$169.82
Median
$208.93
Typical High
$426.58
BCBS Wyoming
Setting
Professional
Modifier
55 · Aftercare only
Typical Low
$47.86
Median
$60.26
Typical High
$123.03
Cigna
Setting
Facility
Modifier
None
Typical Low
$380.19
Median
$380.19
Typical High
$380.19
Cigna
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$41.69
Typical High
$416.87
United
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$81.28
Typical High
$141.25

Where Wyoming sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Wyoming· 7th of 51

$240

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.