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SEPT9 Methylation Blood Test for Colon Cancer

Wyoming rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$240

Typical negotiated rate. In Wyoming, July 2026.

Insurers have agreed to pay about $240 for this service. The price depends on where it is billed: about $295 from a physician practice, and about $126 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$295$240 to $617
FacilityA hospital or hospital-owned outpatient department$126$105 to $191

How much rates vary

Facilitymedian $126 · 10th to 90th $76 to $380Professionalmedian $295 · 10th to 90th $83 to $617
$50.0$100.0$200.0$500.0facility $126professional $295

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Aetna
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
BCBS
Setting
Facility
Modifier
Global
Typical Low
$104.71
Median
$104.71
Typical High
$125.89
BCBS
Setting
Professional
Modifier
Global
Typical Low
$239.88
Median
$295.12
Typical High
$616.60
Cigna
Setting
Facility
Modifier
Global
Typical Low
$380.19
Median
$380.19
Typical High
$380.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$39.81
Median
$41.69
Typical High
$416.87
United
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$75.86
Typical High
$75.86
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$81.28
Typical High
$141.25

Where Wyoming sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Wyoming $240 · 4th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.