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SEPT9 Methylation Blood Test for Colon Cancer

New York rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$162

Typical negotiated rate. In New York, July 2026.

Insurers have agreed to pay about $162 for this service. The price depends on where it is billed: about $129 from a physician practice, and about $316 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 9 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$129$45.71 to $191
FacilityA hospital or hospital-owned outpatient department$316$191 to $447

How much rates vary

Facilitymedian $316 · 10th to 90th $135 to $525Professionalmedian $129 · 10th to 90th $33 to $309
$100.0$1.0K$10.0K$100.0Kfacility $316professional $129

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$316.23
Typical High
$524.81
Aetna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$154.88
Typical High
$346.74
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$33.11
Typical High
$275.42
CDPHP
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$190.55
Typical High
$190.55
CDPHP
Setting
Professional
Modifier
Global
Typical Low
$141.25
Median
$190.55
Typical High
$190.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$407.38
Typical High
$501.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$147.91
Typical High
$616.60
Emblem Health
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$316.23
Typical High
$741.31
Emblem Health
Setting
Professional
Modifier
Global
Typical Low
$114.82
Median
$162.18
Typical High
$363.08
Excellus BCBS
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$181.97
Typical High
$338.84
MVP Health Care
Setting
Facility
Modifier
Global
Typical Low
$13.80
Median
$257.04
Typical High
$50,118.72
MVP Health Care
Setting
Professional
Modifier
Global
Typical Low
$63.10
Median
$190.55
Typical High
$269.15
United
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$190.55
Typical High
$288.40
United
Setting
Professional
Modifier
Global
Typical Low
$72.44
Median
$134.90
Typical High
$295.12
Univera
Setting
Facility
Modifier
Global
Typical Low
$93.33
Median
$162.18
Typical High
$204.17
Univera
Setting
Professional
Modifier
Global
Typical Low
$85.11
Median
$181.97
Typical High
$457.09

Where New York sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

New York $162 · 31st of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.