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SEPT9 Methylation Blood Test for Colon Cancer

Indiana rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$158

Typical negotiated rate. In Indiana, July 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $158 from a physician practice, and about $191 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$158$50.12 to $158
FacilityA hospital or hospital-owned outpatient department$191$191 to $380

How much rates vary

Facilitymedian $191 · 10th to 90th $191 to $575Professionalmedian $158 · 10th to 90th $33 to $174
$10.0$50.0$200.0$1.0Kfacility $191professional $158

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$213.80
Typical High
$575.44
Aetna
Setting
Professional
Modifier
Global
Typical Low
$151.36
Median
$158.49
Typical High
$173.78
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$575.44
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$33.11
Typical High
$107.15
CareSource
Setting
Facility
Modifier
Global
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$363.08
Cigna
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$138.04
Typical High
$234.42
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
United
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$81.28
Typical High
$208.93

Where Indiana sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Indiana $158 · 33rd of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.