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SEPT9 Methylation Blood Test for Colon Cancer

Indiana rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$115

Typical negotiated rate. In Indiana, October 2026.

Insurers have agreed to pay about $115 for this service. The price depends on where it is billed: about $83.18 from a physician practice, and about $288 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$83.18$33.11 to $174
FacilityA hospital or hospital-owned outpatient department$288$191 to $575

How much rates vary

Facilitymedian $288 · 10th to 90th $141 to $741Professionalmedian $83 · 10th to 90th $33 to $234
$50$100$200$500$1K$2Kfacility $288professional $83

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$158.49
Median
$288.40
Typical High
$707.95
Aetna
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$158.49
Typical High
$288.40
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$72.44
Median
$79.43
Typical High
$144.54
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$28.84
Median
$31.62
Typical High
$57.54
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$380.19
Typical High
$575.44
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$208.93
CareSource
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$186.21
Typical High
$186.21
Cigna
Setting
Facility
Modifier
None
Typical Low
$125.89
Median
$190.55
Typical High
$549.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$138.04
Typical High
$371.54
Physicians Health Plan of Northern Indiana
Setting
Facility
Modifier
None
Typical Low
$138.04
Median
$478.63
Typical High
$2,187.76
Physicians Health Plan of Northern Indiana
Setting
Professional
Modifier
None
Typical Low
$138.04
Median
$162.18
Typical High
$295.12
United
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$114.82
Typical High
$229.09

Where Indiana sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Indiana· 43rd of 51

$115

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.