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SEPT9 Methylation Blood Test for Colon Cancer

Illinois rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$158

Typical negotiated rate. In Illinois, July 2026.

Insurers have agreed to pay about $158 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$70.79 to $174
FacilityA hospital or hospital-owned outpatient department$295$195 to $398

How much rates vary

Facilitymedian $295 · 10th to 90th $158 to $525Professionalmedian $155 · 10th to 90th $3 to $295
$10.0$100.0$1.0Kfacility $295professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$158.49
Median
$288.40
Typical High
$398.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$158.49
Typical High
$331.13
BCBS
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$338.84
Typical High
$2,398.83
BCBS
Setting
Professional
Modifier
Global
Typical Low
$3.47
Median
$131.83
Typical High
$147.91
Cigna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$446.68
Typical High
$891.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$125.89
Typical High
$295.12
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$275.42
Typical High
$407.38
Hally Health
Setting
Facility
Modifier
Global
Typical Low
$100.00
Median
$100.00
Typical High
$100.00
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$251.19
Typical High
$251.19
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$190.55
Typical High
$380.19
United
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$81.28
Typical High
$165.96

Where Illinois sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Illinois $158 · 34th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.