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SEPT9 Methylation Blood Test for Colon Cancer

Virginia rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$145

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $145 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $324 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$39.81 to $162
FacilityA hospital or hospital-owned outpatient department$324$162 to $479

How much rates vary

Facilitymedian $324 · 10th to 90th $98 to $1,000Professionalmedian $135 · 10th to 90th $33 to $257
$10.0$100.0$1.0K$10.0Kfacility $324professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$407.38
Typical High
$954.99
Aetna
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$162.18
Typical High
$363.08
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$776.25
Median
$1,000.00
Typical High
$1,202.26
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$33.11
Typical High
$58.88
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$147.91
Median
$165.96
Typical High
$186.21
Cigna
Setting
Facility
Modifier
Global
Typical Low
$194.98
Median
$478.63
Typical High
$977.24
Cigna
Setting
Professional
Modifier
Global
Typical Low
$40.74
Median
$107.15
Typical High
$190.55
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$208.93
Typical High
$269.15
Medcost
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$190.55
Typical High
$323.59
Medcost
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$407.38
Sentara
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$190.55
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$81.28
Median
$190.55
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$75.86
Median
$190.55
Typical High
$229.09
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$85.11
Typical High
$141.25

Where Virginia sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Virginia $145 · 42nd of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.