go back

SEPT9 Methylation Blood Test for Colon Cancer

North Carolina rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$155

Typical negotiated rate. In North Carolina, July 2026.

Insurers have agreed to pay about $155 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $170 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$129 to $191
FacilityA hospital or hospital-owned outpatient department$170$155 to $269

How much rates vary

Facilitymedian $170 · 10th to 90th $120 to $646Professionalmedian $155 · 10th to 90th $71 to $251
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $170professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$169.82
Typical High
$645.65
Aetna
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$154.88
Typical High
$251.19
BCBS
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$263.03
Typical High
$537.03
BCBS
Setting
Professional
Modifier
Global
Typical Low
$70.79
Median
$173.78
Typical High
$309.03
Cigna
Setting
Facility
Modifier
Global
Typical Low
$144.54
Median
$416.87
Typical High
$870.96
Cigna
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$89.13
Typical High
$223.87
Medcost
Setting
Facility
Modifier
Global
Typical Low
$70.79
Median
$173.78
Typical High
$302.00
Medcost
Setting
Professional
Modifier
Global
Typical Low
$251.19
Median
$251.19
Typical High
$251.19
United
Setting
Facility
Modifier
Global
Typical Low
$50.12
Median
$100.00
Typical High
$229.09
United
Setting
Professional
Modifier
Global
Typical Low
$41.69
Median
$95.50
Typical High
$154.88
Wellcare
Setting
Facility
Modifier
Global
Typical Low
$912.01
Median
$912.01
Typical High
$912.01
Wellcare
Setting
Professional
Modifier
Global
Typical Low
$954.99
Median
$954.99
Typical High
$1,445.44

Where North Carolina sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

North Carolina $155 · 36th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.