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SEPT9 Methylation Blood Test for Colon Cancer

Ohio rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$87.10

Typical negotiated rate. In Ohio, October 2026.

Insurers have agreed to pay about $87.10 for this service. The price depends on where it is billed: about $81.28 from a physician practice, and about $269 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$81.28$33.11 to $155
FacilityA hospital or hospital-owned outpatient department$269$204 to $417

How much rates vary

Facilitymedian $269 · 10th to 90th $186 to $490Professionalmedian $81 · 10th to 90th $33 to $269
$50$100$200$500$1Kfacility $269professional $81

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$346.74
Typical High
$489.78
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$173.78
Typical High
$239.88
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$69.18
Typical High
$97.72
Aetna
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$154.88
Typical High
$416.87
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$77.62
Median
$77.62
Typical High
$208.93
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.90
Median
$30.90
Typical High
$83.18
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$33.11
Typical High
$239.88
CareSource
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$257.04
Typical High
$257.04
Cigna
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$229.09
Typical High
$794.33
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$87.10
Typical High
$199.53
Medical Mutual of Ohio
Setting
Facility
Modifier
None
Typical Low
$204.17
Median
$239.88
Typical High
$794.33
Medical Mutual of Ohio
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$87.10
Typical High
$199.53
Molina
Setting
Professional
Modifier
None
Typical Low
$131.83
Median
$173.78
Typical High
$239.88
SummaCare
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$229.09
Typical High
$302.00
United
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$173.78
Typical High
$288.40
United
Setting
Professional
Modifier
None
Typical Low
$46.77
Median
$114.82
Typical High
$275.42

Where Ohio sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Ohio· 51st of 51

$87.10

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.