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SEPT9 Methylation Blood Test for Colon Cancer

Iowa rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$186

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $186 for this service. The price depends on where it is billed: about $166 from a physician practice, and about $295 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$166$148 to $331
FacilityA hospital or hospital-owned outpatient department$295$191 to $490

How much rates vary

Facilitymedian $295 · 10th to 90th $148 to $562Professionalmedian $166 · 10th to 90th $115 to $1,259
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $295professional $166

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$147.91
Median
$398.11
Typical High
$562.34
Aetna
Setting
Professional
Modifier
Global
Typical Low
$125.89
Median
$165.96
Typical High
$1,258.93
Cigna
Setting
Facility
Modifier
Global
Typical Low
$389.05
Median
$389.05
Typical High
$389.05
Cigna
Setting
Professional
Modifier
Global
Typical Low
$245.47
Median
$371.54
Typical High
$457.09
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$162.18
Median
$269.15
Typical High
$338.84
Medica
Setting
Facility
Modifier
Global
Typical Low
$165.96
Median
$229.09
Typical High
$512.86
Medica
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$173.78
Typical High
$758.58
Midlands
Setting
Professional
Modifier
Global
Typical Low
$234.42
Median
$251.19
Typical High
$251.19
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$208.93
Typical High
$407.38
United
Setting
Facility
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$426.58
United
Setting
Professional
Modifier
Global
Typical Low
$50.12
Median
$114.82
Typical High
$331.13
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$190.55
Typical High
$190.55

Where Iowa sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Iowa $186 · 19th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.