go back

SEPT9 Methylation Blood Test for Colon Cancer

Maryland rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$145

Typical negotiated rate. In Maryland, July 2026.

Insurers have agreed to pay about $145 for this service. Most negotiated rates run $105 to $162.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $81 · 10th to 90th $81 to $145Professionalmedian $145 · 10th to 90th $55 to $209
$2.0$10.0$50.0$200.0$1.0Kfacility $81professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
Global
Typical Low
$54.95
Median
$144.54
Typical High
$181.97
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$138.04
Median
$138.04
Typical High
$169.82
Cigna
Setting
Professional
Modifier
Global
Typical Low
$43.65
Median
$117.49
Typical High
$338.84
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$229.09
Typical High
$288.40
United
Setting
Facility
Modifier
Global
Typical Low
$81.28
Median
$81.28
Typical High
$144.54
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$87.10
Typical High
$131.83
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$95.50
Median
$95.50
Typical High
$95.50

Where Maryland sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Maryland $145 · 44th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.