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SEPT9 Methylation Blood Test for Colon Cancer

Rhode Island rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$107

Typical negotiated rate. In Rhode Island, October 2026.

Insurers have agreed to pay about $107 for this service. The price depends on where it is billed: about $107 from a physician practice, and about $219 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 4 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$107$61.66 to $145
FacilityA hospital or hospital-owned outpatient department$219$83.18 to $229

How much rates vary

Facilitymedian $219 · 10th to 90th $76 to $257Professionalmedian $107 · 10th to 90th $62 to $200
$50$100$200$500facility $219professional $107

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$61.66
Median
$61.66
Typical High
$61.66
BCBS Rhode Island
Setting
Facility
Modifier
None
Typical Low
$75.86
Median
$218.78
Typical High
$234.42
BCBS Rhode Island
Setting
Professional
Modifier
None
Typical Low
$91.20
Median
$123.03
Typical High
$144.54
Cigna
Setting
Facility
Modifier
None
Typical Low
$144.54
Median
$257.04
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$39.81
Median
$128.82
Typical High
$263.03
United
Setting
Facility
Modifier
None
Typical Low
$229.09
Median
$229.09
Typical High
$229.09
United
Setting
Professional
Modifier
None
Typical Low
$45.71
Median
$109.65
Typical High
$316.23

Where Rhode Island sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Rhode Island· 44th of 51

$107

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.