go back

SEPT9 Methylation Blood Test for Colon Cancer

Pennsylvania rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$155

Typical negotiated rate. In Pennsylvania, October 2026.

Insurers have agreed to pay about $155 for this service. The price depends on where it is billed: about $151 from a physician practice, and about $229 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$151$115 to $162
FacilityA hospital or hospital-owned outpatient department$229$191 to $417

How much rates vary

Facilitymedian $229 · 10th to 90th $155 to $575Professionalmedian $151 · 10th to 90th $79 to $209
$100$1K$10Kfacility $229professional $151

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$154.88
Typical High
$562.34
Aetna
Setting
Professional
Modifier
None
Typical Low
$141.25
Median
$154.88
Typical High
$162.18
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$75.86
Median
$77.62
Typical High
$81.28
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.20
Median
$30.90
Typical High
$32.36
Capital Blue Cross
Setting
Facility
Modifier
None
Typical Low
$331.13
Median
$426.58
Typical High
$5,011.87
Capital Blue Cross
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$151.36
Typical High
$199.53
Cigna
Setting
Facility
Modifier
None
Typical Low
$186.21
Median
$316.23
Typical High
$575.44
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$102.33
Typical High
$288.40
Emblem Health
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$251.19
Typical High
$251.19
Geisinger
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$190.55
Typical High
$190.55
Geisinger
Setting
Professional
Modifier
None
Typical Low
$63.10
Median
$162.18
Typical High
$346.74
Martin's Point
Setting
Facility
Modifier
None
Typical Low
$154.88
Median
$154.88
Typical High
$660.69
Martin's Point
Setting
Professional
Modifier
None
Typical Low
$151.36
Median
$154.88
Typical High
$162.18
Martin's Point
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$75.86
Median
$77.62
Typical High
$81.28
Martin's Point
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$30.20
Median
$30.90
Typical High
$32.36
UPMC Health Plan
Setting
Facility
Modifier
None
Typical Low
$190.55
Median
$208.93
Typical High
$478.63
UPMC Health Plan
Setting
Professional
Modifier
None
Typical Low
$190.55
Median
$208.93
Typical High
$208.93
United
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$190.55
Typical High
$229.09
United
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$95.50
Typical High
$218.78

Where Pennsylvania sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Pennsylvania· 24th of 51

$155

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.