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SEPT9 Methylation Blood Test for Colon Cancer

Oklahoma rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$97.72

Typical negotiated rate. In Oklahoma, October 2026.

Insurers have agreed to pay about $97.72 for this service. The price depends on where it is billed: about $85.11 from a physician practice, and about $178 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$85.11$79.43 to $182
FacilityA hospital or hospital-owned outpatient department$178$145 to $275

How much rates vary

Facilitymedian $178 · 10th to 90th $126 to $525Professionalmedian $85 · 10th to 90th $35 to $955
$50$100$200$500$1Kfacility $178professional $85

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$158.49
Typical High
$177.83
Aetna
Setting
Professional
Modifier
None
Typical Low
$6.03
Median
$141.25
Typical High
$204.17
BCBS Oklahoma
Setting
Facility
Modifier
None
Typical Low
$213.80
Median
$281.84
Typical High
$363.08
BCBS Oklahoma
Setting
Professional
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$181.97
Cigna
Setting
Facility
Modifier
None
Typical Low
$54.95
Median
$524.81
Typical High
$524.81
Cigna
Setting
Professional
Modifier
None
Typical Low
$37.15
Median
$85.11
Typical High
$85.11
Medica
Setting
Facility
Modifier
None
Typical Low
$141.25
Median
$190.55
Typical High
$912.01
Medica
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$114.82
Typical High
$954.99
United
Setting
Facility
Modifier
None
Typical Low
$69.18
Median
$190.55
Typical High
$229.09
United
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$81.28
Typical High
$114.82

Where Oklahoma sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Oklahoma· 49th of 51

$97.72

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.