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SEPT9 Methylation Blood Test for Colon Cancer

Kentucky rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$107

Typical negotiated rate. In Kentucky, October 2026.

Insurers have agreed to pay about $107 for this service. The price depends on where it is billed: about $107 from a physician practice, and about $162 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$107$50.12 to $155
FacilityA hospital or hospital-owned outpatient department$162$155 to $372

How much rates vary

Facilitymedian $162 · 10th to 90th $83 to $389Professionalmedian $107 · 10th to 90th $33 to $380
$50$100$200$500$1Kfacility $162professional $107

Distribution of negotiated rates across all payers (price axis is log-scale). Small sample; interpret with caution. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$83.18
Median
$154.88
Typical High
$162.18
Aetna
Setting
Professional
Modifier
None
Typical Low
$134.90
Median
$154.88
Typical High
$190.55
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$107.15
Median
$107.15
Typical High
$107.15
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$33.11
Median
$70.79
Typical High
$107.15
CareSource
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$194.98
Typical High
$269.15
CareSource
Setting
Professional
Modifier
None
Typical Low
$204.17
Median
$239.88
Typical High
$316.23
Cigna
Setting
Facility
Modifier
None
Typical Low
$147.91
Median
$389.05
Typical High
$457.09
Cigna
Setting
Professional
Modifier
None
Typical Low
$72.44
Median
$933.25
Typical High
$933.25
United
Setting
Professional
Modifier
None
Typical Low
$50.12
Median
$83.18
Typical High
$208.93
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$67.61
Median
$77.62
Typical High
$95.50
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$26.92
Median
$30.90
Typical High
$38.02

Where Kentucky sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Kentucky· 45th of 51

$107

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.