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SEPT9 Methylation Blood Test for Colon Cancer

Colorado rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$200

Typical negotiated rate. In Colorado, July 2026.

Insurers have agreed to pay about $200 for this service. The price depends on where it is billed: about $145 from a physician practice, and about $479 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$145$81.28 to $155
FacilityA hospital or hospital-owned outpatient department$479$257 to $794

How much rates vary

Facilitymedian $479 · 10th to 90th $145 to $977Professionalmedian $145 · 10th to 90th $50 to $204
$50.0$100.0$200.0$500.0$1.0Kfacility $479professional $145

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$120.23
Median
$416.87
Typical High
$912.01
Aetna
Setting
Professional
Modifier
Global
Typical Low
$57.54
Median
$144.54
Typical High
$204.17
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$245.47
Median
$575.44
Typical High
$977.24
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$33.11
Median
$81.28
Typical High
$190.55
Cigna
Setting
Facility
Modifier
Global
Typical Low
$112.20
Median
$125.89
Typical High
$501.19
Cigna
Setting
Professional
Modifier
Global
Typical Low
$37.15
Median
$93.33
Typical High
$275.42
Denver HMP
Setting
Facility
Modifier
Global
Typical Low
$125.89
Median
$190.55
Typical High
$288.40
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$269.15
Median
$275.42
Typical High
$371.54
Select Health
Setting
Facility
Modifier
Global
Typical Low
$199.53
Median
$354.81
Typical High
$407.38
Select Health
Setting
Professional
Modifier
Global
Typical Low
$134.90
Median
$190.55
Typical High
$288.40
United
Setting
Facility
Modifier
Global
Typical Low
$87.10
Median
$190.55
Typical High
$288.40
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$81.28
Typical High
$114.82

Where Colorado sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Colorado $200 · 10th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.