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SEPT9 Methylation Blood Test for Colon Cancer

Michigan rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated October 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$135

Typical negotiated rate. In Michigan, October 2026.

Insurers have agreed to pay about $135 for this service. The price depends on where it is billed: about $135 from a physician practice, and about $182 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$135$83.18 to $182
FacilityA hospital or hospital-owned outpatient department$182$182 to $214

How much rates vary

Facilitymedian $182 · 10th to 90th $174 to $282Professionalmedian $135 · 10th to 90th $50 to $195
$50$100$200facility $182professional $135

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$281.84
Aetna
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$141.25
Aetna
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$57.54
Aetna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$186.21
Typical High
$194.98
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$87.10
Median
$93.33
Typical High
$97.72
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$34.67
Median
$38.02
Typical High
$38.90
BCBS Michigan
Setting
Facility
Modifier
None
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
BCBS Michigan
Setting
Professional
Modifier
None
Typical Low
$128.82
Median
$134.90
Typical High
$134.90
Cigna
Setting
Professional
Modifier
None
Typical Low
$38.90
Median
$72.44
Typical High
$263.03
Health Alliance Plan
Setting
Facility
Modifier
None
Typical Low
$181.97
Median
$181.97
Typical High
$281.84
Health Alliance Plan
Setting
Facility
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$141.25
Health Alliance Plan
Setting
Facility
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$57.54
Health Alliance Plan
Setting
Professional
Modifier
None
Typical Low
$79.43
Median
$112.20
Typical High
$199.53
Health Alliance Plan
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$91.20
Median
$91.20
Typical High
$91.20
Health Alliance Plan
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$36.31
Median
$36.31
Typical High
$36.31
Priority Health
Setting
Professional
Modifier
None
Typical Low
$36.31
Median
$87.10
Typical High
$263.03
United
Setting
Facility
Modifier
None
Typical Low
$114.82
Median
$173.78
Typical High
$229.09
United
Setting
Professional
Modifier
None
Typical Low
$35.48
Median
$50.12
Typical High
$114.82

Where Michigan sits

The same service costs 5.4 times more in Texas than in Ohio. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Michigan· 31st of 51

$135

TX $468OH $87.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.