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SEPT9 Methylation Blood Test for Colon Cancer

Michigan rates for HCPCS 81327

A blood test that looks for a chemical change called methylation affecting the SEPT9 gene. This change is frequently present when colorectal cancer is developing, so finding it in blood flags the need for a closer look at the bowel. It is offered as a colorectal cancer screening option for people who will not undergo other forms of screening.

Rates data updated July 2026.

How much does SEPT9 Methylation Blood Test for Colon Cancer cost?

$182

Typical negotiated rate. In Michigan, July 2026.

Insurers have agreed to pay about $182 for this service. The price depends on where it is billed: about $155 from a physician practice, and about $182 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 6 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$155$115 to $182
FacilityA hospital or hospital-owned outpatient department$182$182 to $229

How much rates vary

Facilitymedian $182 · 10th to 90th $182 to $339Professionalmedian $155 · 10th to 90th $46 to $204
$10.0$20.0$50.0$100.0$200.0$500.0$1.0Kfacility $182professional $155

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$181.97
Median
$181.97
Typical High
$338.84
Aetna
Setting
Professional
Modifier
Global
Typical Low
$45.71
Median
$181.97
Typical High
$229.09
BCBS
Setting
Facility
Modifier
Global
Typical Low
$134.90
Median
$134.90
Typical High
$134.90
BCBS
Setting
Professional
Modifier
Global
Typical Low
$128.82
Median
$134.90
Typical High
$134.90
Cigna
Setting
Professional
Modifier
Global
Typical Low
$38.90
Median
$87.10
Typical High
$295.12
Health Alliance Plan
Setting
Facility
Modifier
Global
Typical Low
$173.78
Median
$181.97
Typical High
$338.84
Health Alliance Plan
Setting
Professional
Modifier
Global
Typical Low
$79.43
Median
$125.89
Typical High
$229.09
Priority Health
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$229.09
Typical High
$436.52
United
Setting
Facility
Modifier
Global
Typical Low
$114.82
Median
$190.55
Typical High
$229.09
United
Setting
Professional
Modifier
Global
Typical Low
$35.48
Median
$50.12
Typical High
$114.82

Where Michigan sits

The same service costs 6.9 times more in Alaska than in California. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Michigan $182 · 20th of 51
AK $437CA $63.10

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.