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Detailed Immune Marker Typing, Class I And II

Connecticut rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$363

Typical negotiated rate. In Connecticut, October 2026.

Insurers have agreed to pay about $363 for this service. Most negotiated rates run $209 to $631.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 5 insurance carriers under federal price transparency rules.

How much rates vary

Facilitymedian $537 · 10th to 90th $355 to $912Professionalmedian $251 · 10th to 90th $178 to $813
$200$500$1Kfacility $537professional $251

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$309.03
Typical High
$380.19
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$354.81
Median
$537.03
Typical High
$912.01
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$177.83
Median
$208.93
Typical High
$891.25
Cigna
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$549.54
Typical High
$1,380.38
Cigna
Setting
Professional
Modifier
None
Typical Low
$229.09
Median
$446.68
Typical High
$851.14
ConnectiCare
Setting
Professional
Modifier
None
Typical Low
$338.84
Median
$457.09
Typical High
$562.34
United
Setting
Professional
Modifier
None
Typical Low
$144.54
Median
$213.80
Typical High
$478.63
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$128.82
Median
$154.88
Typical High
$154.88
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$51.29
Median
$61.66
Typical High
$61.66

Where Connecticut sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Connecticut· 25th of 51

$363

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.