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Detailed Immune Marker Typing, Class I And II

Wisconsin rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$708

Typical negotiated rate. In Wisconsin, October 2026.

Insurers have agreed to pay about $708 for this service. The price depends on where it is billed: about $603 from a physician practice, and about $871 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 10 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$603$355 to $1,380
FacilityA hospital or hospital-owned outpatient department$871$417 to $1,479

How much rates vary

Facilitymedian $871 · 10th to 90th $417 to $2,399Professionalmedian $603 · 10th to 90th $200 to $2,399
$200$500$1K$2K$5Kfacility $871professional $603

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$416.87
Aetna
Setting
Professional
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$7,413.10
Anthem BCBS
Setting
Facility
Modifier
None
Typical Low
$741.31
Median
$891.25
Typical High
$954.99
Anthem BCBS
Setting
Professional
Modifier
None
Typical Low
$169.82
Median
$741.31
Typical High
$2,511.89
Cigna
Setting
Facility
Modifier
None
Typical Low
$870.96
Median
$1,023.29
Typical High
$1,318.26
Cigna
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$954.99
Typical High
$1,071.52
DeanCare
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$2,187.76
Typical High
$2,951.21
DeanCare
Setting
Professional
Modifier
None
Typical Low
$2,089.30
Median
$2,089.30
Typical High
$2,290.87
Medica
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$416.87
Typical High
$758.58
Medica
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$478.63
Typical High
$1,737.80
Network Health
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$537.03
Typical High
$537.03
Network Health
Setting
Professional
Modifier
None
Typical Low
$346.74
Median
$588.84
Typical High
$977.24
Prevea360
Setting
Facility
Modifier
None
Typical Low
$269.15
Median
$416.87
Typical High
$758.58
Quartz
Setting
Professional
Modifier
None
Typical Low
$380.19
Median
$870.96
Typical High
$1,202.26
Quartz
Setting
Professional
Modifier
None
Typical Low
$165.96
Median
$213.80
Typical High
$891.25
Security Health
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$354.81
Typical High
$741.31
Security Health
Setting
Professional
Modifier
None
Typical Low
$354.81
Median
$1,380.38
Typical High
$2,398.83
United
Setting
Facility
Modifier
None
Typical Low
$416.87
Median
$416.87
Typical High
$416.87
United
Setting
Professional
Modifier
None
Typical Low
$154.88
Median
$281.84
Typical High
$1,318.26
2 more rates with less common billing modifiers

A modifier changes what was billed, for example a reduced or repeated service. Each of these modifiers carries under 10% of the published rates for this code. Modifier combinations, and modifiers with fewer than 30 rates for a carrier, are not listed.

Insurance Carrier
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$208.93
Median
$208.93
Typical High
$3,715.35
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$83.18
Median
$83.18
Typical High
$1,479.11

Where Wisconsin sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Wisconsin· 3rd of 51

$708

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.