go back

Detailed Immune Marker Typing, Class I And II

Iowa rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$347

Typical negotiated rate. In Iowa, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $309 from a physician practice, and about $589 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$309$269 to $708
FacilityA hospital or hospital-owned outpatient department$589$347 to $912

How much rates vary

Facilitymedian $589 · 10th to 90th $269 to $1,000Professionalmedian $309 · 10th to 90th $229 to $2,291
$200$500$1K$2Kfacility $589professional $309

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$812.83
Typical High
$1,000.00
Aetna
Setting
Professional
Modifier
Global
Typical Low
$229.09
Median
$302.00
Typical High
$2,290.87
Cigna
Setting
Facility
Modifier
Global
Typical Low
$933.25
Median
$933.25
Typical High
$933.25
Cigna
Setting
Professional
Modifier
Global
Typical Low
$446.68
Median
$660.69
Typical High
$831.76
Hally Health
Setting
Professional
Modifier
Global
Typical Low
$295.12
Median
$602.56
Typical High
$2,187.76
Medica
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$416.87
Typical High
$977.24
Medica
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$426.58
Typical High
$1,737.80
Midlands
Setting
Professional
Modifier
Global
Typical Low
$426.58
Median
$457.09
Typical High
$457.09
Oscar Health
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$371.54
Typical High
$741.31
United
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$758.58
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$239.88
Typical High
$933.25
Wellmark
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$346.74

Where Iowa sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Iowa· 33rd of 51

$347

AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.