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Detailed Immune Marker Typing, Class I And II

Florida rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$309

Typical negotiated rate. In Florida, July 2026.

Insurers have agreed to pay about $309 for this service. The price depends on where it is billed: about $302 from a physician practice, and about $776 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$302$282 to $339
FacilityA hospital or hospital-owned outpatient department$776$347 to $1,288

How much rates vary

Facilitymedian $776 · 10th to 90th $302 to $2,042Professionalmedian $302 · 10th to 90th $209 to $490
$10.0$100.0$1.0Kfacility $776professional $302

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$309.03
Median
$977.24
Typical High
$2,344.23
Aetna
Setting
Professional
Modifier
Global
Typical Low
$263.03
Median
$302.00
Typical High
$489.78
Ambetter
Setting
Professional
Modifier
Global
Typical Low
$213.80
Median
$213.80
Typical High
$213.80
AvMed
Setting
Facility
Modifier
Global
Typical Low
$302.00
Median
$346.74
Typical High
$407.38
AvMed
Setting
Professional
Modifier
Global
Typical Low
$14.13
Median
$346.74
Typical High
$346.74
Cigna
Setting
Facility
Modifier
Global
Typical Low
$251.19
Median
$371.54
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
Global
Typical Low
$173.78
Median
$295.12
Typical High
$691.83
Florida Blue
Setting
Facility
Modifier
Global
Typical Low
$645.65
Median
$645.65
Typical High
$645.65
Florida Blue
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$208.93
Typical High
$457.09
Molina
Setting
Professional
Modifier
Global
Typical Low
$100.00
Median
$123.03
Typical High
$588.84
United
Setting
Facility
Modifier
Global
Typical Low
$169.82
Median
$309.03
Typical High
$426.58
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$199.53
Typical High
$467.74
Wellpoint
Setting
Professional
Modifier
Global
Typical Low
$91.20
Median
$346.74
Typical High
$346.74

Where Florida sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Florida $309 · 42nd of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.