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Detailed Immune Marker Typing, Class I And II

Florida rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated October 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$282

Typical negotiated rate. In Florida, October 2026.

Insurers have agreed to pay about $282 for this service. The price depends on where it is billed: about $282 from a physician practice, and about $646 from a hospital or other facility.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 7 insurance carriers under federal price transparency rules.

Prices by location type

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$282$200 to $324
FacilityA hospital or hospital-owned outpatient department$646$447 to $646

How much rates vary

Facilitymedian $646 · 10th to 90th $339 to $646Professionalmedian $282 · 10th to 90th $145 to $457
$10$20$50$100$200$500$1Kfacility $646professional $282

Distribution of negotiated rates across all payers (price axis is log-scale). Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
None
Typical Low
$173.78
Median
$309.03
Typical High
$954.99
Aetna
Setting
Professional
Modifier
None
Typical Low
$257.04
Median
$302.00
Typical High
$331.13
Aetna
Setting
Professional
Modifier
52 · Reduced service
Typical Low
$141.25
Median
$147.91
Typical High
$158.49
Aetna
Setting
Professional
Modifier
53 · Discontinued
Typical Low
$56.23
Median
$60.26
Typical High
$64.57
AvMed
Setting
Facility
Modifier
None
Typical Low
$275.42
Median
$346.74
Typical High
$416.87
AvMed
Setting
Professional
Modifier
None
Typical Low
$275.42
Median
$346.74
Typical High
$346.74
Cigna
Setting
Facility
Modifier
None
Typical Low
$251.19
Median
$371.54
Typical High
$1,412.54
Cigna
Setting
Professional
Modifier
None
Typical Low
$173.78
Median
$281.84
Typical High
$707.95
Florida Blue
Setting
Facility
Modifier
None
Typical Low
$645.65
Median
$645.65
Typical High
$645.65
Florida Blue
Setting
Professional
Modifier
None
Typical Low
$208.93
Median
$208.93
Typical High
$457.09
Molina
Setting
Professional
Modifier
None
Typical Low
$100.00
Median
$100.00
Typical High
$588.84
United
Setting
Facility
Modifier
None
Typical Low
$346.74
Median
$346.74
Typical High
$346.74
United
Setting
Professional
Modifier
None
Typical Low
$120.23
Median
$199.53
Typical High
$562.34
Wellpoint
Setting
Professional
Modifier
None
Typical Low
$323.59
Median
$346.74
Typical High
$346.74

Where Florida sits

The same service costs 4.6 times more in Texas than in Alabama. Every bar is a state, most expensive first. Touch or drag across it to read any state, then open that state for its carriers and full range.

Florida· 46th of 51

$282

TX $794AL $174

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.