go back

Detailed Immune Marker Typing, Class I And II

Massachusetts rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$347

Typical negotiated rate. In Massachusetts, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $347 from a physician practice, and about $851 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$347$347 to $380
FacilityA hospital or hospital-owned outpatient department$851$490 to $1,047

How much rates vary

Facilitymedian $851 · 10th to 90th $331 to $1,380Professionalmedian $347 · 10th to 90th $269 to $851
$100.0$1.0K$10.0Kfacility $851professional $347

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$794.33
Typical High
$1,479.11
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$331.13
Typical High
$1,047.13
AllWays Health Partners
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$489.78
Typical High
$1,202.26
AllWays Health Partners
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$354.81
Typical High
$1,148.15
BCBS
Setting
Facility
Modifier
Global
Typical Low
$676.08
Median
$851.14
Typical High
$1,230.27
BCBS
Setting
Professional
Modifier
Global
Typical Low
$323.59
Median
$323.59
Typical High
$338.84
Cigna
Setting
Facility
Modifier
Global
Typical Low
$269.15
Median
$467.74
Typical High
$724.44
Cigna
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$363.08
Typical High
$891.25
Fallon Health
Setting
Facility
Modifier
Global
Typical Low
$83.18
Median
$3,630.78
Typical High
$9,772.37
Fallon Health
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$501.19
Typical High
$588.84
Harvard Pilgrim
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$660.69
Mass General Brigham
Setting
Facility
Modifier
Global
Typical Low
$316.23
Median
$489.78
Typical High
$1,202.26
Mass General Brigham
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$354.81
Typical High
$1,148.15
United
Setting
Facility
Modifier
Global
Typical Low
$281.84
Median
$346.74
Typical High
$562.34
United
Setting
Professional
Modifier
Global
Typical Low
$208.93
Median
$346.74
Typical High
$831.76

Where Massachusetts sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Massachusetts $347 · 29th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.