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Detailed Immune Marker Typing, Class I And II

Virginia rates for HCPCS 81378

This genetic test identifies a person's specific immune-system marker genes across both the Class I and Class II groups together, at a highly detailed level of resolution. These markers play an important role in how the immune system recognizes foreign material, and precise matching of them between a donor and recipient is especially important for bone marrow and stem cell transplants. The detailed level of testing allows for more precise matching than a basic-level test.

Rates data updated July 2026.

How much does Detailed Immune Marker Typing, Class I And II cost?

$347

Typical negotiated rate. In Virginia, July 2026.

Insurers have agreed to pay about $347 for this service. The price depends on where it is billed: about $275 from a physician practice, and about $468 from a hospital or other facility. The two figures are alternatives, not parts of one bill.

These are rates insurers have negotiated with providers, not the amount a patient is billed. What you owe depends on your plan's deductible and coinsurance. Based on rates published by 8 insurance carriers under federal price transparency rules.

Where it's billed changes the price

Billed byTypicalRange
Physician practiceA doctor's office, clinic or independent provider$275$200 to $347
FacilityA hospital or hospital-owned outpatient department$468$347 to $851

How much rates vary

Facilitymedian $468 · 10th to 90th $339 to $1,820Professionalmedian $275 · 10th to 90th $170 to $776
$10.0$100.0$1.0K$10.0Kfacility $468professional $275

Distribution of negotiated rates across all payers (price axis is log-scale). Each curve is scaled to its own total: facility and professional rates are different services, shown together to compare where they cluster. Need provider-level prices or 24+ months of history? Contact us.

Rates by insurance carrier

Insurance Carrier
Aetna
Setting
Facility
Modifier
Global
Typical Low
$323.59
Median
$758.58
Typical High
$2,089.30
Aetna
Setting
Professional
Modifier
Global
Typical Low
$257.04
Median
$323.59
Typical High
$954.99
Anthem BCBS
Setting
Facility
Modifier
Global
Typical Low
$346.74
Median
$346.74
Typical High
$1,380.38
Anthem BCBS
Setting
Professional
Modifier
Global
Typical Low
$169.82
Median
$169.82
Typical High
$288.40
CareFirst
Setting
Professional
Modifier
Global
Typical Low
$316.23
Median
$1,412.54
Typical High
$2,137.96
Cigna
Setting
Facility
Modifier
Global
Typical Low
$354.81
Median
$851.14
Typical High
$1,778.28
Cigna
Setting
Professional
Modifier
Global
Typical Low
$190.55
Median
$234.42
Typical High
$724.44
Kaiser Permanente
Setting
Professional
Modifier
Global
Typical Low
$346.74
Median
$380.19
Typical High
$478.63
Medcost
Setting
Facility
Modifier
Global
Typical Low
$288.40
Median
$489.78
Typical High
$691.83
Medcost
Setting
Professional
Modifier
Global
Typical Low
$275.42
Median
$275.42
Typical High
$724.44
Sentara
Setting
Facility
Modifier
Global
Typical Low
$331.13
Median
$467.74
Typical High
$10,000.00
Sentara
Setting
Professional
Modifier
Global
Typical Low
$331.13
Median
$467.74
Typical High
$10,000.00
United
Setting
Facility
Modifier
Global
Typical Low
$229.09
Median
$346.74
Typical High
$562.34
United
Setting
Professional
Modifier
Global
Typical Low
$144.54
Median
$208.93
Typical High
$467.74

Where Virginia sits

The same service costs 3.1 times more in Alaska than in Delaware. Every bar is a state, most expensive first. Pick one to see its carriers and full range.

Virginia $347 · 35th of 51
AK $776DE $251

Median negotiated rate in each state, from every insurer that publishes one. States where no insurer publishes a rate for this service are not shown.